Dr. Mark Albers, a neurologist at the McCance Center for Brain Health at Harvard - affiliated with the Massachusetts General Hospital, says it is not all that uncommon for seniors to experience symptoms of brain fog when taking certain medications for the first time. He explains medications can affect memory more in aging adults as “older people tend to metabolize drugs more slowly, making them more sensitive to medications and more vulnerable to side effects.”
Other reasons medications cause more problems in seniors are they often take larger doses of a drug and more frequently as well as take several drugs to treat one health condition. Moreover older people may have a weakened blood-brain barrier. This barrier works to block toxins and other harmful substances including drugs from entering the brain, which may account for some memory problems.
Sleep medications are one of the common medications that can be problematic. Over-the-counter sleeping aids can contain anticholinergic drugs, which are known to impair cognitive function, and some prescription sleep drugs diminish activity in parts of the brain involved in transferring short-term memories to long-term memory. Pain medications can additionally result in memory problems. The good news is once patients stop taking sleep or pain meds, modify the dose or replace the drug with a better option, many of the problems go away.
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Source: health.harvard.edu/mind-and-mood/stuck-in-a-brain-fog-look-in-your-medicine-cabinet
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